I've got a 295 35 18 on mine, on a 10" wheel. They're pretty much flush with the fender lip and I have less than 1/2" between the inside of the tire and the sheet metal. No quad shocks. If you worked on the sheet metal in the wheel well a little, I'd think you could go to a 305 or maybe a 315, but they'll need to stick all the way out to the edge of the fender for sure. They'll rub if the car is very low, so rolled fenders are a must.
88 LX - 302, Vortech V3 SI, Powerpipe, 80mm ProM, 50lb injectors, 75mm TB, Edelbrock RPM II, Edelbrock Heads, Harland Sharp rockers, BBK 1 3/4" LTs, X pipe, Flowmasters, 3.73 gears, 5 lug / 4 wheel disc, FR500 wheels. 529rwhp / 492rwtq