You didn't mention your piston & rod setup, what's it like other than larger diameter pistons?
Did the machine shop polish away your counterweights.
Check the easy stuff first. Ign. timing, transposed plug wires, distributor orientation, but you've prolly done all that already, then see if your #1 piston hits TDC when it is supposed to in relation to your #1 valves doin' their thing. You'd be sprized how far off that can be and the engine still starts.
One nasty thing, I had a timing chain stretch and jump a tooth or two on a 72 Gremlin X 304, stupid nylon timing sprockets. The thing idled like a A/A Funnycar, but would not run for snot. I am surprised it even started. Come to think of it, I am surprised it EVER started.

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Bone Stock '07 GT 4.6, Redfire w/ parchment leather, Automatic.
If it looks right, it is right, and I decide if it looks right. Paraphrasing Sir Sydney Camm (of Hawker aircraft IIRC)