Cody, I'm using AFR 165's on my 289 with a CompCams XE262 (~$200 for the kit), not sure how you ended up with a $400 cam, sounds like a roller cam instead of flat tappet hyd.
Here's mine:
COMP Cams® - Cam Details
Your valves shouldn't hit the heads with 1.60/1.90 AFR 165's, if you went with the 185's which have 2.02 valves which is where interference usually comes in. How big a cam are you looking at?
The XE262 is a midrange since it just tops .500 lift, do you plan to go past .550 lift?
Depending on your compression ratio/deck height, head cc the only safe way to tell is to put some clay on top of the pistons, install the heads and turn the crank to measure squish.
I haven't started my motor yet but expect to be happy with performance and the ability to still drive as a DD with an AOD and 3.50:1 Tracloc.
Jon
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'67 Coupe 289 C4, Candyapple red w/red deluxe int., PS, ext. decor group, light group, foxbody seats.
Next to install> stroked 333, AOD, 9" w/3.50:1, PDB.
'09 Black Warriors In Pink with glass roof - the wifes Mustang.
"If it ain't broke, I haven't fixed it yet" -Jon