The 351W is the same design/familiy as a 221-302, 5.0. It can use the same heads, cam, timing chain, timing cover, water pump and
trans.
The main difference is the block. The 351 block is taller, not the heads. Plus you can not use a 302 oil pan on a 351W. The rear seal area is larger on the 351W.
I believe Weiand has a supercharger for the 351W, Or B&M.
There are single plane manifolds modified for injection use. Coast High Performance (CHP, Probe) has one. Plus there are a few places that have the parts to convert a manifold to injection.