Who ever told you high compression + Nitrous is bad is
High or low compression ratios can work with nitrous provided the proper balance of nitrous and fuel made.
Spray is used in low compression stock type motors to Pro-Modifieds, which often exceed 15 to 1. Generally, the higher the compression ratio, the more ignition retard.
Nitrous does not cause detonaton. Detonation is the result of too little fuel present during combustion (lean) or too low of an octane of fuel. Too much ignition advance also causes detonation.
If your not sure how nitrous works, here is a quick summary.
The nitrogen part super cools the incoming fuel/air mix, making it very dense, then the oxygen aids in burning hotter, which requires an extra fuel supply to richen up the dense mix so the extra oxygen doesn't burn the piston with the extra combustion heat.
When this super dense fuel mix is ignited, the extra oxygen makes it burn quick and hot, and you get the kick in the pants burst of power to the rear wheels.

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1995 Forrest Green Mustang GT 1/226 Made
*UPR CAI*, *Pro-M 75mm*, *FRPP 65mm TB w/SVO elbow*, *Extrude Honed GT40 Tubular Intake*, *Extrude Honed GT40 Iron Heads w/multi angle valve job*, *Cobra 1.7's*, *Stock Cam*, *FRPP Stainless Shortys*, *Prochamber*, *Flowmaster Stainless Catback*, *3.73's.*, *Hughes Performance 2500 Converter*, *Performance Automatic AODE*
251RWHP/284RWTQ with a Radical Racing Tune.