I'm biased since I use a centrifugal but at times, I wish I had a bit more hp/tq below 4,000 rpm. Most of the time my driving is light to light and when on the freeway, there is never any room or time to blast to 6,000rpm. On the other hand, I'm not always into boost so I'm guessing I'm not putting too much stress on the internals. My gas mileage (which sucks regardless) is helped out a bit but that really doesn't worry me. I didn't mod the car to get good gas mileage

If I ever need more power, I simply step on the gas pedal another inch or so, and maybe downshift, to get into my most effective rpm range, 4-6000rpm. From 3-4 grand, the pull isn't bad and would probably be a match for most non-modified cars out there. From 4-6 grand, my car pulls like a banshee.
Regardless, every set-up has its place and if its matched to a good combo, like the 2003 Cobra, then it's a hard to beat platform. I'm still not sold so much on the roots but a twin screw design like Kenne Bell would be a blast. Spools up like a turbo, full boost at low rpm's, but probably (IMO) much less expensive for initial purchase and tuning (brand new at least).