They may bolt up, but getting them to work is a completely different matter. I don’t think the bores of the 4.6 block are big enough to clear the Coyote valves. You could possibly sleeve the 4.6 block to have a big enough bore but at that point you just spent more than a 5.0 crate motor costs. And that doesn’t take into account the possible oil/water passage differences, possible front cover issues, etc.
Waiting on 2019 GT500 2012 GT Vert Brembo - Stock-ish 2012 F-150 FX4 EcoBoost 4x4 406rwhp/522rwtq. The most powerful EB F-150 on the planet?
2007 GT-TSR/Stops/Turns/Custom Everything/3.4L Whipple Crusher/1000hp SOLD