They do not run under pressure the way an engine does.
The vent is for the expansion of the differential oil as it heats up, which as it expands, air is expelled, and oil if necessary.
However, if the vent is blocked, there is a pressure build up which could contribute to causing leaking seals.
2012 Shelby American Mustang GTS 580rwhp 485 ft/lbs Grabber Blue White Stripes
Ford Whipple, 5.0L, Tremec XL Magnum, MGW, Centerforce DYAD clutch, Boss 302 Torsen w/4:10s, 302R EPAS, Eibach Coil Overs, Fays 2 Watts Link, Dynotech DS, Shelby UCAs/LCAs, Wilwood brakes 6 piston 4 piston, Drake Bump Steer, heavy duty cooling, welded axle tubes, Interior Package, GT4 wheels, Borla Touring axlebacks, GT500 rear valence w/parking sensors, and airbag cover signed by Carroll Shelby.