Jacked up this one this weekend to replace the fuel filter (in the middle above the pumpkin BTW), as someone mentioned in another thread, duals back, dual cats, then the Y pipe. Interesting. Other than sound I'm not sure why any exhaust changes would be worth it as you say. Regarding the sound, My V10 is like a V6, they just don't sound like a V8. I replaced the Flowmaster on the V10 to a stocker because the sound really sucked (IMO). I do notice a slight power loss but the truck is silent now.
I think I'm done with this one for now, just a toy until my son gets his license.