I'm glad to hear you figured out what system you want to run, I think that'll sound great!
1. 2.5" exhaust is absolutely fine on a V6!
2. The only problem you're going to run into is running a 2.5" exhaust and trying to run a 3" muffler. If you're going to weld them in, I'm sure they could use a reducer which should allow you to run that size piping! If the exhaust shop can get it done, I don't see a problem with it.
I hope this helps! Please let me know if you have any questions or need some assistance in the near future.
-Dan